The complement system is a key component of innate and adaptive immunity and therefore acts as a vital defense against invading pathogens. Deficiencies in the complement system are associated with ...
A new review by Dr. Ruyuan Wang and an international team of researchers explores the complex interactions between the innate and adaptive immune systems, shedding light on regulatory mechanisms in ...
Immunity is defined as an organism’s ability to protect itself from anything that it does not recognize as self, such as a pathogen or toxin. Innate immunity, also known as genetic or natural immunity ...
The complement system has more than 50 soluble and membrane-bound proteins. In innate and adaptive immunity, complement is essential for eliminating foreign pathogens and apoptotic cells. It is also ...
This new article publication from Acta Pharmaceutica Sinica B, discusses how the use of a radiation-based immunogenic vaccine combined with a macrophage “checkpoint inhibitor” can boost innate and ...
Immunotherapy is increasingly becoming standard therapy in cancer, with technology, such as checkpoint inhibitors and cell therapy, raising the efficacy bar in many forms of the disease. But the ...
In a recent review published in the journal Cell, a group of authors explored existing immunological assumptions to better understand unresolved phenomena and improve vaccine design, autoimmune ...
The BCG vaccine protects against tuberculosis, but by inducing trained immunity it also protects against many more respiratory infections. International research led by the Radboudumc shows how this ...
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