Covariate-adaptive randomization represents an advanced methodology in the design of clinical trials, ensuring a balanced distribution of prognostic factors among treatment groups. This approach ...
Randomization have proven to be an efficient way of reducing bias and thus is widely used in clinical trials. Randomization ensures that subject allocation is balanced across treatment group and is ...
DSP-0390, an oral emopamil binding protein (EBP) inhibitor, in patients with recurrent high-grade glioma: A first-in-human, phase 1 study. Background: GBM AGILE (Glioblastoma Adaptive, Global, ...
Noninvasive Application of Alternating Electric Fields in Glioblastoma: A Fourth Cancer Treatment Modality Adaptive designs are aimed at introducing flexibility in clinical research by allowing ...
Twice-yearly mass distribution of azithromycin to children is a promising intervention to reduce childhood mortality in sub-Saharan Africa. The World Health Organization recommended restricting ...