The research group led by Professor Hitoshi Kurumizaka, Laboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, has revealed how the DNA repair ...

The ability to explore the genome on a sub-nucleosome level promises to lead to new discoveries about how chromatin structure is linked to epigenetics ...

The ability to explore the genome on a sub-nucleosome level promises to lead to new discoveries about how chromatin structure is linked to epigenetics ...

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D structure of DNA is important for controlling cell-specific gene expression ...

Genomic DNA is organized into chromatin via nucleosomes, regulating its accessibility for critical biological processes such as transcription, replication, and epigenetic modification. The dynamic ...

A recent study has shed light on the transcriptional regulatory mechanisms of Penicillium expansum, the fungal culprit behind blue mold disease in fruits. By mapping chromatin accessibility at ...

Researchers from the University of Chicago (IL, USA) have reported that unstable, or ‘noisy’, chromatin enables cells to take on different roles in the body. This flexibility can support the immune ...

These modifications increase chromatin accessibility, influencing growth, differentiation, and ion transport, with contrasting effects on normal and colorectal cancer cells. Study: Short-chain fatty ...