A manuscript recently published in Nature Methods by the Trono and Aebischer labs introduces a new transcriptionally regulated, lentivirus-based transgene delivery system functional in cultured cells ...

Apoptosis has been defined as a genetic death program that leads to ordered destruction of cellular components while it preserves membrane integrity. Most proapoptotic signaling cascades involve ...

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Drug-inducible systems allowing the control of gene expression in mammalian cells are invaluable tools for genetic research, and could also fulfill essential roles in gene- and cell-based therapy.