In this paper, we formalize the application of multivariate meta-analysis and meta-regression to synthesize estimates of multi-parameter associations obtained from different studies. This modelling ...

Multivariate analyses such as principal component analysis were among the first statistical methods employed to extract information from genetic markers. From their early applications to current ...

Genome-Wide Association Studies (GWAS) have transformed human genetics by identifying thousands of loci associated with complex traits and diseases. Yet, individual GWAS are often underpowered, and ...