At a virtual conference in November 2020, the winner of a biennial protein-structure-prediction challenge was announced: AlphaFold. Created by Google DeepMind, this computational tool had blown its ...
理化学研究所(理研)生命医科学研究センタートランスクリプトーム研究チームのアレッサンドロ・ボネッティ客員研究員、ピエロ・カルニンチチームリーダーらの研究チームは、細胞核内のRNAとゲノムDNA(クロマチン[1] )の相互作用をゲノム全体で調べる ...
-実験室での生命誕生過程の再現に向けて- 理化学研究所(理研)生命機能科学研究センター高機能生体分子開発チームの李佩瑩(リ・ペエイ)研究員、田上俊輔チームリーダーらの国際共同研究チームは、正電荷を持つペプチド[1] 凝集体がRNA[2] を吸着し ...
Two separate laboratory breakthroughs have produced RNA molecules that can build copies of themselves or assemble functional structures without any help from proteins or DNA. These results offer the ...
RIKEN researchers have discovered how an enzyme modifies gene expression by targeting certain stretches of messenger RNA ...
When RNA molecules are synthesized by cells — a critical process in the creation of proteins and other cellular functions — they typically undergo a series of “folding” events that determine their ...
RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...
Neurons have a "hibernation mode." Scientists discover how brain cells use RNA tentacles to lock their protein factories together to survive when energy is low.
New research shows that lipid nanoparticles used in mRNA vaccines may deliver RNA more effectively when their structure is disorganised.
Researchers show how LGP2 binds viral RNA ends, moves along the strand, and helps MDA5 form filaments that amplify antiviral signaling. The findings clarify an early defense step and may inform ...