The FDA has released a draft guidance outlining how drug developers can validate new approach methodologies (NAMs) as alternatives to animal testing in preclinical drug development. The guidance, ...
The U.S. Food and Drug Administration is actively steering drug developers away from traditional animal studies and toward human-biology-based testing methods for monoclonal antibody programs. The ...
FDA’s NAM framework emphasizes context of use, human biological relevance, technical characterization, and fit-for-purpose ...
Non-animal testing methods could save drugmakers time and money, officials say ...
Cell and gene therapies require novel quality control methods due to their complex, variable nature and limited shelf life, challenging traditional pharmaceutical testing approaches. Manufacturers ...