The randomized ISAT demonstrated the superiority of endovascular treatment in patients with ruptured intracranial aneurysms considered suitable for either clipping or coiling. A later publication ...
Phase II trial designs that ignore between-patient heterogeneity and do not allow for treatment-subgroup interactions may produce very large false positive and false ...
Copyright: © 2005 Elsevier Ltd. Published by Elsevier Ltd. Large pragmatic trials provide the most reliable data about the effects of treatments, but should be ...
2 Center for Clinical Epidemiology and Evidence-Based Medicine, West China Hospital, Sichuan University, Chengdu, China 3 Basel Institute for Clinical Epidemiology and Biostatistics, University ...
Two Bayesian clinical trial designs that perform subgroup-specific decision making and inference based on elicited utilities of patient outcomes are reviewed. The first is a randomized comparative ...
The values of the subgroup-variable, which is specified in the chart statement, indicate how the observations in the input data set (a DATA=, HISTORY=, or TABLE= data set) are arranged into rational ...
27 Department of Anesthesia and Pain Medicine, Hospital for Sick Children, Toronto, Ontario, Canada 28 Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, ...
Efforts to improve reporting clinical trial results have led to the development of guidelines such as those recommended by the CONSORT group. 3,4 Transparent and comprehensive reporting of subgroup ...
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