Regular physical activity provides evidence of being an effective way to relieve symptoms of anxiety and depression in people ...

The literature on physician-mediated interventions to reduce costs is scant and provides little guidance on effective strategies. Objectives: Provider organizations are increasingly entering ...

In this video interview, Marc Buyse, ScD, founder and CEO of IDDI, examines the most common threats to trial data reliability, including opaque methodologies, synthetic controls, and the limits of ...

Stop falling for misleading headlines. Understand the difference between correlation and causation, and learn how researchers prove real scientific facts.

Stay current in clinical research with Applied Clinical Trials, providing expert insights, regulatory updates, and practical strategies for successful clinical trial design and execution.

A personalized peptide vaccine slashed prostate-specific antigen levels by as much as 99.6% in some men with advanced ...

Two phase 2b studies in atopic dermatitis and alopecia areata reported positive outcomes, demonstrating clinically meaningful ...

For the primary endpoint, patients treated with povetacicept achieved a 52.0% reduction from baseline in proteinuria as measured by 24-hour urine protein to creatinine ratio (UPCR) and achieved a ...

This useful study supplements previous publications of willed attention by addressing a frontoparietal network that supports internal goal generation. The evidence is solid in analyzing two datasets ...

Researchers explore the links between birth control and depression, highlighting potential risks among adolescents.

The arterial vasculature is the second most frequently calcified structure in the human body after the skeleton. Calcification of the aorta and aortic valves occurs in most individuals in westernized ...

To our knowledge, this analysis is the largest EHR-based study for identifying drug repurposing candidates for ALS. We identified several drugs that warrant further assessment as therapeutic options ...